Public Health
The cardiovascular fitness level of cancer survivors is not affected by many standard cancer therapies, say researchers from Georgetown University Medical Cancer. That is the finding of a new observational study to be presented today at the American College of Sports Medicine in Seattle.
Bayer HealthCare LLC., Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX), OSI Pharmaceuticals, Inc. (Nasdaq: OSIP) and Roche today announced the initiation of a Phase 3 trial examining Nexavar(R) (sorafenib) tablets in combination with Tarceva(R) (erlotinib) tablets as a potential new treatment option for patients with advanced hepatocellular carcinoma (HCC), or primary liver cancer.
BioCis Pharma Ltd., a privately-held drug development company with its headquarters in Turku, Finland, has started Phase I clinical testing of ProtoCure(TM) intravesical instillation solution, a novel anti-cancer drug for urinary bladder cancer. ProtoCure is based on a new mechanism of action discovered and developed by BioCis Pharma which effectively prevents cancer growth and proliferation locally.
Since the implementation of the Massachusetts health insurance law in 2006, more residents have health coverage and increased access to care, but rising health care costs combined with the current economic recession could undermine some of the law"s successes, according to the third annual "Update on Health Reform in Massachusetts" report by the Urban Institute, the Boston Globe reports. The study was funded by the Blue Cross and Blue Shield of Massachusetts Foundation, the Robert Wood Johnson Foundation and the Commonwealth Fund, and published in the journal Health Affairs.For the report, Sharon Long of the Urban Institute and colleagues surveyed about 4,000 Massachusetts adults in 2007 and 2008 and compared their health care habits with those of residents surveyed in 2006 -- just after the law went into effect. Researchers found that although there were initial gains in health care affordability, there are now some signs that an increasing number of state residents are reporting problems paying for medical bills, and an increasing number of people -- especially lower-income residents -- not seeking care because of costs (Lazar, Boston Globe, 5/28). One in five adults reported being told in the past 12 months that a physician or clinic was not accepting new patients or would not see patients with their type of insurance (Sack, New York Times, 5/28). Lower-income residents had more difficulties finding a physician than higher-income residents, with 24% of residents enrolled in state-subsidized health plans, saying they were told that a physician did not accept their insurance, compared with 7% of residents with private coverage (Boston Globe, 5/28). Additional Findings
An increasing number of U.S. residents "are on the outside looking in to a world of [medical] progress and discovery that is denied to them because they cannot afford quality health care," Senate Health, Education, Labor and Pensions Committee Chair Edward Kennedy (D-Mass.) writes in a Boston Globe opinion piece. He writes that he is "thrilled" to be working with lawmakers on health reform legislation "that will build on what"s already working and fix what"s broken" in the current system.According to Kennedy, health reform legislation "will include five major elements":
"Origins and Strategies for Addressing Ethnic and Racial Disparities in Pharmaceutical Therapy: The Health-Care System, the Provider, and the Patient," National Minority Quality Forum: The report -- by Richard Levy, a health care consultant and former vice president of the National Pharmaceutical Council; Robert Like, professor and director of the Center for Healthy Families and Cultural Diversity of the UMDNJ-Robert Wood Johnson Medical School; and Harry Shabsin, a private-practice psychologist -- looks at how appropriate medications for a variety of diseases often are under-prescribed, over-prescribed, or mis-prescribed among minorities. The report looks at disparities in treatment of minority patients with cardiovascular disease, asthma, psychiatric illness, pain and other conditions and finds disparities in access to medications through insurance programs, in the prescribing of medications and in adherence to medication regimens. The report offers ways to improve prescribing and use of medications among diverse communities (National Minority Quality Forum release, 5/12).
Brits taking advantage of last-minute credit crunch deals to tropical destinations could be seriously risking their health, according to a survey of over 1,000 UK travellers.1
Drs. Timothy Halliday and Sally Kwak, economics professors at the University of Hawaii at Manoa, recently published a paper in Economics and Human Biology titled, "Weight Gain in Adolescents and Their Peers." The article examines trends in adolescent body mass index (BMI) in a nationally representative dataset.
Oxidative stress has been linked to aging, cancer and other diseases in
A new blood test used in combination with a conventional prostate-specific antigen (PSA) screening sharply increases the accuracy of prostate cancer diagnosis, and could eliminate tens of thousands of unneeded, painful, and costly prostate biopsies annually, according to a study led by researchers at Dana-Farber Cancer Institute.
In response to industry demand, VIBevents is proud to announce the launch of the industry"s first virtual clinical trials event, ClinicalTrialsArena.com, which will bring together the leading decision makers within the pharma and biotech industries.
UK researchers who reviewed pooled clinical trial data covering 95,000 people concluded that there was no net benefit to healthy people taking
The popular belief that healthy eating starts at home and that parents" dietary choices help children establish their nutritional beliefs and behaviors may need rethinking, according to a study by researchers at the Johns Hopkins Bloomberg School of Public Health. An examination of dietary intakes and patterns among U.S. families found that the resemblance between children"s and their parents" eating habits is weak. The results are published in the May 25, 2009, issue of Social Science and Medicine.
CuraGen Corporation (Nasdaq: CRGN) announced plans for three data presentations from its ongoing clinical trials of CR011-vcMMAE, an antibody-drug conjugate that targets GPNMB, in patients with advanced breast cancer and melanoma at the 2009 Annual Meeting of the American Society of Clinical Oncology (ASCO) in Orlando, Florida.
Researchers at the University of Southern California (USC) and USC Norris Comprehensive Cancer Center will present breakthrough research in a number of researchstudy areas at the 2009 American Society of Clinical Oncology (ASCO) annual meeting in Orlando, Florida.
UroToday.com - This updated review of tadalafil (Cialis), one of the three available phosphodiesterase type 5 (PDE5) inhibitors that revolutionized the treatment of erectile dysfunction (ED), analyzes its latest clinical studies. Tadalafil"s most unique and identifying characteristic is its long half-life of 17.5 hours, compared with 4 hours for sildenafil (Viagra) and vardenafil (Levitra).
Two of the world"s leading Alzheimer"s researchers have co-edited a book critically synthesizing the major new developments in the diagnosis and treatment of Alzheimer"s disease. Building upon a 2007 Alzheimer"s disease conference held in Chile, George Perry, dean of the College of Sciences at The University of Texas at San Antonio (UTSA) and Ricardo B. Maccioni, neurology professor at The University of Chile Medical School have edited "Current Hypotheses and Research Milestones in Alzheimer"s Disease," a 254-page text written by academics and medical doctors. The book focuses on the most promising hypotheses that illuminate the path to more effective treatment.
A new, international study found that the combination of two drugs delays disease progression for patients with advanced non-small cell lung cancer (NSCLC). Results from the Phase III "ATLAS" trial were presented today by Dr. Vincent Miller of Memorial Sloan-Kettering Cancer Center (MSKCC) at the American Society of Clinical Oncology Annual Meeting.
Researchers from the University of Pittsburgh Cancer Institute (UPCI) have identified eight genes that help predict a melanoma patient"s response to treatment. The new findings are being presented at the 45th annual meeting of the American Society of Clinical Oncology (ASCO), May 29 to June 2, in Orlando, Fla.
The Nebraska Legislature on Wednesday voted to advance a bill (L.B. 675) that would require abortion providers who perform ultrasounds on women seeking the procedure to tell women that a view of the fetus will be available and display the screen in a way that the image can be easily seen, the AP/Lincoln Journal Star reports. The bill also would require the state to compile a list of clinics that offer no-cost ultrasound services. State Sen. Brenda Council (D) criticized that particular provision, saying it would force the state Department of Health and Human Services to spend more taxpayer money.Lawmakers advanced the bill by voice vote after approving an amendment to clarify language surrounding the qualifications of health professionals performing ultrasounds. Advocates for the bill claim it would provide more information to women seeking abortion procedures, while opponents of the bill argue that it would allow the government to interfere in a private procedure. The bill faces a final vote before going to Gov. Dave Heineman (R). If the bill becomes law, Nebraska would join more than a dozen states that have similar laws, the AP/Journal Star reports (Ortiz, AP/Lincoln Journal Star, 5/27).
Congressional lawmakers who are crafting a plan to overhaul the U.S. health care system might be able to look to state health insurance programs in Massachusetts and Tennessee for ideas, the AP/Minneapolis Star Tribune reports. Health reform legislation modeled after Massachusetts" near-universal health insurance law "is likely to emerge" in Congress, "although details remain unsettled," the AP/Star Tribune reports. The plan also could include components of Tennessee"s CoverTN program, which charges beneficiaries who smoke or are overweight higher premiums. Lawmakers in the Senate already have discussed a lifestyle tax funding mechanism, such as taxes on alcohol and sugary beverages. According to AP/Star Tribune, Massachusetts "chose to cover virtually everyone," while Tennessee "chose to get just a few more people bare-bones insurance at a budget price with limits on how much plans would pay for hospital stays."Alan Weil of the National Academy for State Health Policy said, "The belief that we should all have health insurance coverage is broadly held," but "there are tremendous differences around the country in beliefs on how to achieve that goal." He added, "We learn from Massachusetts that a bold objective matters. If it can be sustained, that"s terrific," and "[i]t would be nice if you had a southern state that had achieved universal coverage and did it in a different way, but we don"t have that" (Johnson, AP/Minneapolis Star Tribune, 5/28).
USA Today: It is "gratifying" that Republicans last week introduced a health care proposal because "the simple fact that it exists might improve chances" for bipartisan negotiations, a USA Today editorial states. According to the editorial, the plan -- which would replace the current tax exemption of employer-provided insurance with a refundable tax credit for all families and individuals, regardless of their employment status -- is "no cure-all," but is a "serious proposal that merits serious consideration." The editorial states, "For all those who say the Republican Party is out of ideas, on the issue of health coverage, at least, its proposal is bolder than what the Democrats have offered." However, the editorial notes that both Republicans and Democrats "have identified more groundbreaking ideas, and they are not entirely incompatible." The editorial concludes, "[L]et the debate begin. The only unacceptable approach is the status quo" (USA Today, 5/29).
Patients undergoing treatment for advanced head and neck cancers may respond well to the addition of gefinitib to chemotherapy, according to a study sponsored by the Eastern Cooperative Oncology Group and chaired by Ethan Argiris, M.D., associate professor of medicine, University of Pittsburgh School of Medicine, and co-leader of the Head and Neck Cancer Program of the University of Pittsburgh Cancer Institute (UPCI). The results were disclosed at the 45th annual meeting of the American Society of Clinical Oncology (ASCO) on May 30 in Orlando, Fla.
A landmark follow-up study found that heart attack survivors who receive implanted cardioverter defribillators (ICDs) live longer the longer they have them, according to the results of late-breaking clinical trail presented at the annual Scientific Sessions of the Heart Rhythm Society.
A case report written by Dr Francesco Natale and his colleagues, from the Second University of Naples and Monaldi Hospital, Naples, Italy, reports on the dangers of stimulant chewing gums containing caffeine. The report published in this week÷´s edition of The Lancet describes the story of a teenage boy hospitalized after excessive consumption of this type of product. The authors warn about the high risks of stimulant chewing gums that are widely available to children.
A new article published in Elsevier"s journal Bioscience Hypotheses suggests that our feelings in our lifetime can affect our children.
A series of free seminars, one in Belfast, has been organised to raise awareness of women"s health and rights in a 21st century where new biomedical techniques allow surrogate motherhood, test-tube babies, organ transplants and other medical developments.
The Alabama Department of Public Health has confirmed its first novel H1N1 influenza cases in
U.S. researchers who worked with Romanian colleagues to create a highquality,
MDS Nordion, a leading global provider of medical isotopes and
The lead article in a special supplement on clinical handover in the Medical Journal of Australia relates a tragic case in which an elderly man died for want of effective handover.
A survey of trauma patients reported in the Medical Journal of Australia has found that compensation-related factors are significant predictors of health care utilisation.
The Regulatory Affairs Professionals Society (RAPS), the world"s largest
Paroxysmal nocturnal hemoglobinuria (PNH) cells are present in the majority of patients with myelodysplastic syndromes (MDS), aplastic anemia (AA), and other bone marrow failure syndromes (BMF), according to interim results from 5,285 patients enrolled in the EXPLORE trial. EXPLORE (EXamination of PNH, by Level Of CD59 on REd and white blood cells) is the first large multicenter study to determine the frequency of PNH cells in these patient populations using a central laboratory conducting a high sensitivity test for PNH cells. The findings from EXPLORE will be presented tomorrow at the 45th Annual Meeting of the American Society of Clinical Oncology (ASCO). The EXPLORE trial was sponsored by Alexion Pharmaceuticals, Inc. (Nasdaq:ALXN).
With consumer genetics becoming more of a reality to the average consumer and direct-to-consumer (DTC) genetics tests becoming more available, thought leaders, experts and DTC companies will convene in Boston on June 9-11 for the first annual Consumer Genetics Conference to move the issues to the forefront and demystify this emerging field. Preeminent leaders from government, healthcare, biotechnology and diagnostic fields, will examine consumer genetics, including its practical realities and complex policy considerations; speakers and companies will present new advances and information on available genetic tests and developments in this field. The conference is open to all who are curious, impacted by, and interested in consumer genetics, including consumers (http://www.consumergeneticsconference.com).
The Society for Clinical Ophthalmology (SCO) is now working with UK-based Consultant Ophthalmologist, Mr Som Prasad, to supplement ophthalmic surgical training with an online forum that offers videos and online discussions of surgical techniques.
Scientists have developed a new "risk index" that helps predict which individuals over the age of 65 may go on to develop dementia.
Neurobiological Technologies, Inc. (Nasdaq: NTII) (NTI(R)) announced that Celtic Pharmaceutical Holdings L.P. (Celtic Pharma) has announced the results from its Phase 3 Clinical Program for XERECEPT(R) in patients with edema associated with brain tumors and from preclinical studies of XERECEPT in brain tumor models.
Provectus Pharmaceuticals, Inc. (OTC Bulletin Board: PVCT), a development-stage oncology and dermatology biopharmaceutical company, has announced interim data from the first 40 subjects in its Phase 2 clinical trial for the treatment of metastatic melanoma. PV-10 treatment was well tolerated and caused selective tumor destruction in the majority of subjects. Additional data on untreated tumors corroborated observations of a possible bystander effect seen during earlier Phase 1 testing. These data were presented today at the American Society of Clinical Oncology 2009 Annual Meeting, Abstract #9060, entitled "Chemoablation of melanoma with intralesional rose bengal (PV-10)," in the General Poster Session.
A dog born with a deadly disease that prevents the body from using stored sugar has survived 20 months and is still healthy after receiving gene therapy at the University of Florida - putting scientists a step closer to finding a cure for the disorder in children.
With healthcare expenses and despite rising unemployment, the vitamin industry is seeing significant growth. Code Nutrition, a leader in personalized, high quality nutritional supplements, is helping people cut health care costs while maintaining or improving their health, by providing supplements based on personalized genetic testing and lifestyle information.
Unwed pregnant teens and twenty-somethings who attend or have graduated from private religious schools are more likely to obtain abortions than their peers from public schools, according to sociological research published in the June issue of the Journal of Health and Social Behavior.
Infants and young toddlers with obstructive sleep apnea and sleep disordered breathing experience significant improvement following surgical treatment of the ailment, according to an invited article in the June 2009 issue of Otolaryngology-Head and Neck Surgery.
Researchers have identified a gene that is overexpressed in up to 20 percent of breast cancers and that could be blocked in the lab by a currently available blood pressure drug, according to a new study from the University of Michigan Comprehensive Cancer Center.
The New Zealand Medical Students" Association (NZMSA) welcomed the allocated funding for increased medical student numbers and doctor retention in the Government"s budget.
A program aimed at reducing criminal behavior in juvenile justice teens has yielded a surprising side benefit. The program is also reducing the teens" rate of pregnancy, according to a new study out this week.
Monkeys playing a game similar to "Let"s Make A Deal" have revealed that their brains register missed opportunities and learn from their mistakes.
A new study has confirmed that 1 per cent of children aged between 5- and 9-years-old have an existing diagnosis on the autistic spectrum. The research, published in the June issue of the British Journal of Psychiatry, was carried out by the Autism Research Centre at Cambridge University.
A team led by scientists at The Institute of Cancer Research (ICR) compared the genes of 730 men who had developed testicular cancer with the genes of healthy men. They found many of the men who had suffered cancer shared common DNA variants on chromosomes 5, 6 and 12 that the healthy men did not have.
Patients with esophageal cancer who require surgery may benefit from having minimally invasive surgery instead of an open esophagectomy, or removal of the esophagus, according to a University of Pittsburgh Cancer Institute (UPCI) phase II study. The results will be presented May 31 at the 45th annual meeting of the American Society of Clinical Oncology (ASCO) in Orlando, Fla.
In what is believed to be the first U.S. study designed to prevent anxiety disorders in the children of anxious parents, researchers at the Johns Hopkins Children"s Center have found that a family-based program reduced symptoms and the risk of developing an anxiety disorder among these children.
- 0 confirmed cases in Wales.
The Royal College of Anaesthetists, the professional body representing anaesthesia in the UK, is introducing an interactive e-Learning re to support training and professional development in anaesthesia. The programme will be launched by the President of the College, Dr Judith Hulf, at its annual College Tutors conference on 11 June, 2009.
Spending hours taking a high-pressure aptitude test may make people feel mentally fatigued, but that fatigue doesn"t necessarily lead to lower test scores, according to new research published by the American Psychological Association. If anything, performance might actually improve on a longer test, the study found.
It"s hard to miss the huge eye of a squid. But now it appears that certain squids can detect light through an organ other than their eyes as well.
A study published in the June 2009 issue of the Journal of Thoracic Oncology determined several predictors of a positive lung cancer diagnosis after having an abnormal chest x-ray. Dr. Martin Carl Tammemagi of Brock University in Ontario and his team of US researchers examined the chest radiographs of 12,314 individuals obtained through the National Cancer Institute"s Prostate Lung Colorectal Ovarian Cancer Screening Trial (PLCO). They found that older age, lower education levels and a longer smoking history were all associated with a "true positive" diagnosis for lung cancer in those individuals with an abnormal screening chest radiograph.
Treating a common heart rhythm disorder by burning heart tissue with a catheter works dramatically better than drug treatments, a major international study has found.
Insurance companies, "the industry that gets credit for helping to kill the Clinton administration"s health care overhaul 15 years ago," are now "striking a conciliatory tone as it faces the most serious attempt to overhaul the system since that effort collapsed," CQ Politics reports. With low favorability ratings and Democrats in control of the federal government, "insurers know they aren"t in a good bargaining position" this time around. They have already offered concessions, including providing "insurance in the individual markets to everyone, without regard to who is sick," and not "charging people who are ill higher rates and cut health care costs." But they"ve also been ""careful to structure their offers in such a way that appears significant but does not overpromise." An individual mandate for all Americans and an end to health screening for applicants could offer "a win-win outcome, one that will benefit not just patients but potentially the profits of the industry as well." But "perhaps the biggest motivation for insurers to deal now is that they fear what might happen if they don"t" - the "creation of a government-run plan that would be more attractive to the public and siphon off customers" (Adams, 6/1).
BioLineRx Ltd. (TASE:BLRX), a clinical stage drug development company, today announced positive preliminary results from the ongoing phase I/II clinical trial designed to assess the safety and feasibility of BL-1040, the first injectable device designed to address cardiac remodeling, in 20- 30 patients at several sites in Germany and Belgium. To date, 15 patients were successfully treated with BL-1040 with no complications. Moreover, six months follow up results from the first 5 patients show BL-1040"s efficacy in preventing cardiac remodeling and preserving cardiac function.
Virginia Commonwealth University researchers have identified a gene that may play a key role in regulating tumor progression in neuroblastoma, a form of cancer usually found in young children. Scientists hope the finding could lead to an effective therapy to inhibit the expression of this gene.
ZymoGenetics, Inc. (NASDAQ:ZGEN) announced positive final results from a Phase 2 clinical trial in patients receiving 2nd or 3rd line therapy for advanced renal cell carcinoma with the combination of recombinant Interleukin 21 (IL-21) and Nexavar® (sorafenib) tablets. The combination demonstrated considerable clinical benefit, with an overall response rate (as assessed by an independent review) of 21%, a disease control rate of 82%, and progression-free survival (PFS) of 5.7 months in this heavily pretreated population. Results were presented at the American Society of Clinical Oncology meeting.
Depomed, Inc. (NASDAQ:DEPO) announced that it has completed enrollment of the Phase 3 clinical trial of DM-1796 for the treatment of post-herpetic neuralgia.
Using a lawn mower can be as routine as bike riding or barbeques during spring and summer. But often, people find themselves in terrifying situations with these seemingly safe household machines. In fact, 200,000 people - 16,000 of them children - are injured in lawn mower-related accidents each year, the U.S. Consumer Product Safety Commission reports. However, lawn mowers don"t "attack" on their own. Most injuries - such as severed fingers and toes, limb amputations, broken bones, burns and eye injuries - are caused by careless use and can be prevented by following a few simple safety tips.
Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, has announced that the US Food and Drug Administration (FDA) has approved a change to the prescribing information for its once-daily Attention Deficit Hyperactivity Disorder (ADHD) treatment VYVANSE® (lisdexamfetamine dimesylate) CII, to include supplemental data that demonstrated significant ADHD symptom control in children aged 6 to 12 from the first time point measured (1.5 hours) through 13 hours postdose. VYVANSE is now the first and only oral ADHD stimulant treatment to have 13-hour postdose efficacy data for pediatric patients included in its product labeling.
StemCells, Inc. (NASDAQ:STEM) announced plans to present data from its Phase I clinical trial of its proprietary HuCNS-SC® product candidate (purified human neural stem cells) at the 12th International Congress on Neuronal Ceroid Lipofuscinoses (NCL) being held June 3 - 6, 2009 in Hamburg, Germany. Stephen Huhn, MD, FACS, FAAP, vice president and head of the Company"s CNS program, is scheduled to present the data on Saturday, June 6.
Genta Incorporated (OTCBB: GNTA.OB) announced preliminary results from its ongoing clinical study of tesetaxel, a leading oral taxane in the Company"s investigational drug portfolio. The new data show a favorable safety profile with a low incidence of serious adverse events, along with objective responses that have been observed at less than the maximally tolerated dose (MTD). The data are featured in a presentation today at the annual meeting of the American Society of Clinical Oncology (ASCO) in Orlando, FL.
A health workers" strike has caused Benin to indefinitely delay a polio vaccination campaign, part of a regional effort taking place in several West African countries, IRIN reports. The Benin campaign was due to start on May 29.
Mike Tomlinson - husband of Jane Tomlinson CBE backs free and flexible carers programme.
Nigeria Releases 57M Polio Vaccines, Aims To Increase Vaccine Coverage
Plexxikon Inc. today announced preliminary data from a Phase 1 clinical study investigating PLX4032 (R7204). PLX4032 is a novel, oral and highly selective drug that targets the BRAFV600E cancer-causing mutation that occurs in most melanomas and about eight percent of all solid tumors. In patients whose cancer harbors this mutation and who were treated with therapeutic doses of PLX4032, tumor shrinkage and extended progression-free survival have been observed. Currently, two extension studies are being conducted in mutation-positive melanoma and colorectal cancer patients. Following the initial positive findings announced today, larger clinical trials to support a registration program for product approval are targeted to start later in 2009. Plexxikon and Roche are co-developing PLX4032 under their 2006 license and collaboration agreement.
A group of Senate Democrats will meet with President Obama today to discuss overhauling health care, The New York Times reports.
Several of the country"s largest liberal groups said they were prepared to spend $82 million to promote President Obama"s health care reform agenda, the Boston Globe reports. "Joining the effort are two major labor organizations, the AFL-CIO and Change to Win; Health Care for America Now, a coalition of healthcare providers, consumer groups, and activists; MoveOn.org, the massive online activist organization; and other groups that claim a total of 30 million members."
When should a parent schedule a comprehensive eye assessment for a baby? Clinical research has shown that at 6 months, the average baby has reached a number of critical developmental milestones, making this an appropriate age for the first eye and vision assessment.
The American Society of Gene Therapy recently honored three researchers as Outstanding New Investigators in the field of gene therapy.
British researchers on Monday requested the WHO "publicly condemn homeopathy as a treatment for serious diseases, such as HIV/AIDS, TB and malaria," amid growing concern that some patients are dying as a result of choosing homeopathy over effective medicines, the Mail & Guardian reports. "The WHO works with national organisations that promote homeopathy and other alternative medicines in their public health programmes," according to the Mail & Guardian.
Dr Alexis Willett, Head of Policy & Involvement at Breakthrough Breast Cancer, says:
Varian Medical Systems (NYSE: VAR) will be demonstrating its full range of brachytherapy cancer treatment equipment and software at the American Brachytherapy Society meeting in Toronto, Canada, from May 31 to June 2. Varian"s exhibit will include the new BrachyVision™ Acuros™ system, which offers a significantly more accurate* way of calculating the dosimetry of cancer treatments.
Research from a survey by Tesco Dental Insurance has revealed Brits are finding it increasingly difficulty to find an NHS dentist. The results also show that rising dental costs are putting people off visiting the dentist.
As swine flu spread from Mexico to Texas and then fanned out farther in the United States, Americans began to alter their behavior. Families kept children home from school, postponed trips to the mall, and stayed home instead of eating out. In so doing, the American population may have inadvertently altered the behavior of the pathogen itself.
Dr. Dev GnanaDev, president of the California Medical Association, issued the following statement after Gov. Arnold Schwarzenegger called on the state Legislature to swiftly enact his proposed budget cuts.
Researchers at Penn State College of Medicine, working with biochemists, geneticists and clinicians at the University of Bern, Switzerland and in the United Kingdom, have discovered an enzyme that has a key role in inflammatory bowel disease (IBD). The team, co-led by Judith Bond, Ph.D., Distinguished Professor and Chair of Biochemistry and Molecular Biology at Penn State College of Medicine, and Daniel Lottaz, Department of Rheumatology and Clinical Immunology at the University of Bern, Switzerland, could potentially lead to therapies to help the half-a-million Americans affected by ulcerative colitis and Crohn"s disease, collectively referred to as IBD.
New research findings published by Dr Metin Basoglu, Head of Section of Trauma Studies at King"s College London and the Istanbul Centre for Behaviour Research and Therapy, examines the psychological impact of war captivity, "cruel, inhuman, and degrading treatment" (CIDT) and physical torture. Findings revealed that being held captive in a hostile and life-threatening environment, deprivation of basic needs, sexual torture, psychological manipulations, humiliation, exposure to extreme temperatures, isolation, and forced stress positions appear to cause more psychological damage than physical torture.
A closer look at regulatory and clinical concerns with generic immunosuppression medications in thoracic transplantation is required, according to an educational advisory by the International Society for Heart and Lung Transplantation (ISHLT) in the July 2009 issue of The Journal of Heart and Lung Transplantation, published by Elsevier.
A new study published by the American Society of Plastic Surgeons reveals that one of the most common conditions caused by Rheumatoid Arthritis (RA) is best treated surgically, sooner rather than later. Patients with RA frequently experience a debilitating condition known as metacarpophalangeal joint disease, which is usually treated by replacing the knuckle joints with solid silicone joints. However, this treatment (and others like it) has spurred great disagreement between hand surgeons and rheumatologists regarding the indications, timing and perceived outcomes of the procedure; rheumatologists tend to refer late-stage patients for surgery whereas hand surgeons believe that earlier intervention can yield more positive outcomes.
Three patients at NewYork-Presbyterian Hospital/Columbia University Medical Center were among the first in the United States to be implanted with a next-generation artificial heart pump called the DuraHeart™ Left-Ventricular Assist System. The surgeries took place earlier this year. NewYork-Presbyterian/Columbia is one of only three centers in the U.S. currently enrolling patients in a clinical trial studying the device.
New research published by the National Institute for Health Research Health Technology Assessment (NIHR HTA) programme has found that while ibuprofen and paracetamol is more effective when used together when treating fever in pre-school children, ibuprofen should be used first as this will reduce the temperature quicker.
Researchers affiliated with Natura Therapeutics, Inc., Tampa, Florida, and the University of South Florida (USF) have jointly received a one-year, $110,000 Small Business Innovation Research (SBIR) grant from the National Institutes of Health"s (NIH) National Center for Complementary and Alternative Medicine to continue studying TeaMem™, a compound made from green tea.
Traumatic brain injury - not heart disease, stroke or cancer - is the number one cause of death and disability in people under 45. Each year, some 1.5 million Americans, including soldiers, athletes, the elderly and children, sustain head injuries, and nearly half of them will be hospitalized and treated in an emergency room or intensive care unit.
An over-the-counter prostate cancer test kit could be coming to a pharmacy near you, thanks to the collaborative work of a University of Central Florida chemist and M.D. Anderson Cancer Center Orlando researchers.
Researchers from the Brigham and Women"s Hospital and Harvard Medical School in Boston have released a 22-year study that reports Hispanic patients have poorer outcomes following infrainguinal bypass grafting for the treatment of peripheral arterial disease (PAD). Results showed that of all the study participants, Hispanics had a higher rate of bypass graft failure and amputation after revascularization compared to Caucasians. In an analysis that accounted for a myriad of important variables affecting limb salvage after bypass, Hispanic ethnicity was found to be independently predictive of eventual amputation. Details of the study appear in the Society for Vascular Surgery"s(R) June 2009 issue of the Journal of Vascular Surgery(R).
Although Supreme Court nominee Sonia Sotomayor"s confirmation hearings are more than a month away, "it"s easy to predict how they will go," New York Times columnist Ross Douthat writes. Douthat predicts that Senate Judiciary Committee members "will attempt to divine Sotomayor"s position on a variety of controversial topics," such as abortion rights, and in "a series of polite, evasive answers, the nominee will feign a studious neutrality on almost every issue that could come before her during what"s likely to be decades as one of the most powerful women in the world." According to Douthat, the "deeper stakes" that likely will be ignored are that "Sotomayor will be joining a high court that"s gradually become a kind of extra legislative body." He cites research from Harvard Law School professor Jed Shugerman showing that the court over roughly the past 50 years has invalidated both state and federal statutes at an unprecedented rate. Douthat also points to data from Evan Caminker of the University of Michigan showing that in one eight-year period, the court invalidated 16 federal laws in 5-4 votes, something that occurred only 25 times in the previous two centuries. Douthat writes that "settling so many vexing controversies with 5-to-4 votes -- effectively making Anthony Kennedy the nation"s philosopher king -- is an awfully poor way to run a republic."Douthat continues that the "modern court"s most enduringly controversial power grabs -- with Roe v. Wade leading the way -- were usually the work of liberal justices" but that "in practice, the main divide between liberal and conservative judges tends to be over the responsibilities of the federal government, not judicial activism per se." He writes, "There are bipartisan ways that the Court could be reined in, and the legislative branch reinvigorated," including the idea of a supermajority rule that would require a 6-3 vote to overturn federal legislation. This idea "might spur the court toward greater consensus, and perhaps greater modesty as well," according to Douthat. Another possibility would be to implement 12-year term limits, he says. Douthat concludes that these suggestions would not "reduce the Supreme Court"s power directly, but it would help us see the court for what it has become -- a deeply political institution, as fallible as any other, and answerable, when all is said and done, to us" (Douthat, New York Times, 6/2).
Terrence Higgins Trust is using this year"s National Condom Week (18-24 May) as an opportunity to promote safer sex. The aim of the initiative is to raise awareness of the importance of condom use to prevent sexually transmitted infections and unplanned pregnancies.
The Food and Drug Administration is taking steps towards greater openness. The Associated Press reports that FDA Commissioner Margaret Hamburg "announced Tuesday she has created a task force to make recommendations on how the agency can release more information in such areas as drug evaluation and enforcement matters. She wants a report in six months." Deputy Commissioner Joshua Sharfstein will head the task force, which will represent all of the FDA"s major divisions as well as its law enforcement branch. It will hold two public meetings with the first on June 24. "The FDA has long operated under strict confidentiality rules," the AP reports, and in opening up information, one sensitive issue will be what to do with unpublished clinical trial data from drug manufacturers. Despite such concerns, "Hamburg said she believes the need for secrecy may have been taken too far, and is harming the FDA"s credibility within the medical community and among consumers" (Alonso-Zaldivar, 6/2).
June 1, 2009: In a new study, young children and their adult caregivers uttered fewer vocalizations, used fewer words and engaged in fewer conversations when in the presence of audible television. The population-based study is the first of its kind completed in the home environment, guided by lead researcher Dimitri A. Christakis, MD, MPH, director of the Center for Child Health, Behavior and Development at Seattle Children"s Research Institute and professor of pediatrics at the University of Washington School of Medicine. "Audible Television and Decreased Adult Words, Infant Vocalizations, and Conversational Turns" was published in the June 2009 issue of Archives of Pediatrics & Adolescent Medicine.
Researchers at the University of Tennessee Health Science Center (UTHSC) are recruiting participants for a national clinical study of medication that could slow the progression of Parkinson"s disease. The study, referred to as "QE3," will examine the effectiveness of the research medication Coenzyme Q10 (CoQ). During the study, investigators will administer high doses of CoQ to participants 30 years of age or older with early stage Parkinson"s disease to reduce the speed of their physical decline. The research is sponsored by the National Institute of Neurological Disorders and Stroke, a division of the National Institutes of Health (NIH), and will be conducted by the Parkinson Study Group, an international council of physicians and researchers experienced in caring for Parkinson"s patients and studying the disease.
Why The Health Care Rush? - The Wall Street Journal
The new H1N1 swine flu virus claimed the life of a 20-year old Chicago woman on Saturday, one day after giving birth to a baby via Cesarean
Stem cells play a role in heart muscle rejuvenation by attracting cells from the body that develop into heart muscle cells. They have been successfully used to halt or reverse cardiac injury following heart attack, but not to prevent injury before it occurs.
Joseph F. Finn, Jr., C.P.A. ("Finn"), announced today that there has been promising initial interest from pharma companies in the intellectual property of Prospect Therapeutics, Inc. ("Prospect").
MedImpact researchers and Health Alliance Medical Plans, a MedImpact client, presented findings from an important new study that evaluates the impact of value-based benefit design (VBBD) on adherence to diabetes medications. Study results show that implementation of a VBBD program that reduced copayment by almost fifty percent for diabetic medications resulted in significantly improved medication adherence.
New Phase III study results presented for the first time today at the ninth annual American Transplant Congress 2009 (ATC) demonstrate that doubling the duration of preventive therapy ("prophylaxis") with Valcyte (oral valganciclovir), significantly reduces the incidence of CMV disease by 56% in high-risk kidney transplant patients within the first year post-transplant.(1)
Data from 7 prucalopride trials are being presented at the Digestive
Registration for the American Association of Kidney Patients" (AAKP) 36th Annual National Convention is now open. The Convention takes place Sept. 3-5 at the Hyatt Regency Denver in Denver, Colo. The Annual Convention provides patients, family members and health care professionals the opportunity to learn about important issue affecting kidney patients. During this three-day event, attendees participate in educational sessions for those with chronic kidney disease (CKD) to long-term dialysis and transplant patients. Participants also learn about various treatments for each stage of kidney disease.
This paper investigates 26 patients with painful metal-on-metal resurfacing arthroplasties and describes three tests for the investigation of the phenomenon. The tests are metal artefact-reduction MRI, 3-D CT measurement of the position of the component and inductively-coupled plasma mass spectrometry.
Stress may indeed be a direct contributor to childhood obesity. That"s according to a new Iowa State University study finding that increased levels of stress in adolescents are associated with a greater likelihood of them being overweight or obese.
Research published on 1st March 2009 investigates whether "simultaneous bilateral sequential total hip replacement (THR) would increase the rate of mortality and complications compared with unilateral THR", for both low and high risk patients.
A novel species of bacteria with cholesterol-busting properties has been discovered by scientists at the Universidad Complutense de Madrid, Spain. Dr Oliver Drzyzga and colleagues isolated the new bug, called Gordonia cholesterolivorans, from sewage sludge. Their findings are reported in the current issue of the International Journal of Systematic and Evolutionary Microbiology.
A new review published in the Journal of Human Nutrition and Dietetics assessed whether certain modifications in diet have a beneficial effect on the prevention of prostate cancer. Results suggest that a diet low in fat and red meat and high in fruits and vegetables is beneficial in preventing and treating prostate cancer.
Despite the efforts of college students to quit smoking, recent research conducted by Joyce M. Wolburg at Marquette University suggests that an extended trial and error period is necessary. Given that most college students begin smoking in high school, another study by faculty at HEC Montreal and University of Texas at San Antonio provides insights into how graphic cigarette warning labels impact intentions of American and Canadian teens. Both studies appear in the Summer 2009 issue of the Journal of Consumer Affairs.
A protein related to aggressive cancers can actually improve the efficacy of gemcitabine at treating pancreatic cancer, according to a Priority Report in Cancer Research, published by researchers at Thomas Jefferson University.
A new University of Illinois study of families adopting from foster care revealed significant declines in professional services and social support over the first three years of adoptive family life, even though parents indicated that they need continued assistance.
Latent HIV genes can be "smoked out" of human cells. The so-called "shock and kill" technique, described in a preclinical study in BioMed Central"s open access journal Retrovirology, might represent a new milestone along the way to the discovery of a cure for HIV/AIDS.