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Morning People And Night Owls Show Different Brain Function: University Of Alberta Study
Scientists at the University of Alberta have found that there are significant differences in the way our brains function depending on whether we"re early risers or night owls.
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They Are Young And Need The Job: A Second Chance For Dangerous T-cells
The immune system"s T-cells react to foreign protein fragments and therefore are crucial to combating viruses and bacteria. Errant cells that attack the body"s own material are in most cases driven to cell death. Some of these autoreactive T-cells, however, undergo a kind of reeducation to become "regulatory T-cells" that keep other autoreactive T-cells under control. A group led by immunologist Professor Ludger Klein of LMU Munich has now shown that the developmental stage of an autoreactive T-cell is decisive to its ultimate destiny. Young autoreactive T cells are very readily reeducated into regulatory T-cells. Under identical conditions, however, older T cells become fully activated and can cause damage they are in a way resistant to reeducation. "We now intend to study at the molecular level what makes a T-cell accessible for reeducation," said Klein, "because then it may be possible to convert even normal adult T-cells, which can be obtained easily and in great numbers from blood. Possibly, they could then be used as regulatory T-cells in therapies for autoimmune diseases such as type-1 diabetes or multiple sclerosis: these are diseases that are triggered by uncontrolled autoreactive T-cells." (PNAS, 10 June 2009)
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Chinese Women Join Global Breast Cancer Trial
Breast cancer patients have for the first time been recruited from China to take part in an international trial of breast radiotherapy.
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Washington Post Interviews Atul Gawande

The Washington Post"s Ezra Klein spoke with surgeon and writer Atul Gawande. Klein writes: "Gawande"s New Yorker article comparing the medical systems of El Paso and McAllen, Tex., has been a definitional piece in the health reform conversation. President [Barack] Obama has repeatedly invoked it. Senators have talked about it. The media have embraced it. I spoke to Gawande this afternoon about the fallout from his article, the problem of revenue-driven medicine, and whether a public plan would make a difference." For instance, Klein asks: "Do you think much that we"re hearing in the political conversation is responsive to the issues you pointed out?" Gawande: "The Washington debate -- there are smart reasons to think about including a public option in the mix, but we have not been thinking hard enough about how we control costs and make a better system. I think it"s achievable in about 10 to 15 years, and maybe even faster. I can tell you three things that will transform McAllen overnight. But CBO doesn"t score them" (Klein, 6/23). This information was reprinted from kaiserhealthnews.org with kind permission from the Henry J. Kaiser Family Foundation. You can view the entire Kaiser Daily Health Policy Report, search the archives and sign up for email delivery at kaiserhealthnews.org. © Henry J. Kaiser Family Foundation. All rights reserved.


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