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EpiCept Releases New Data Demonstrating Long-Term Durability Of Ceplene In Sustaining Leukemia-Free Survival
EpiCept Corporation (Nasdaq and OMX Nordic Exchange: EPCT) has released new long-term data showing that the use of Ceplene® when administered in conjunction with low-dose interleukin-2 (IL-2) provides durable protection from leukemia relapse in patients with Acute Myeloid Leukemia (AML), based on a minimum of six years of follow-up. These data will be presented on June 6, 2009 at the European Hematology Association"s (EHA) 14th Congress in Berlin, Germany.
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Black Women More Likely To Have Vitamin D Deficiency, Bacterial Vaginosis, Study Finds
Black women are nearly three times as likely as white women to have a vitamin D deficiency, which is linked with an increased risk of the vaginal infection bacterial vaginosis, according to a study published in the June issue of the Journal of Nutrition, the New York Times reports. Black women likely have lower levels of vitamin D because the higher amount of pigment in their skin prevents the body from absorbing the vitamin.For the study, researchers led by Lisa Bodnar, an assistant professor of epidemiology at the University of Pittsburgh, examined 209 white pregnant women and 260 black pregnant women at a Pittsburgh clinic. More than half of the women had low levels of vitamin D, the study found. Women whose vitamin D levels were 50 nanomoles or less had a 26% increased risk of BV, while women whose vitamin levels were less than 20 nanomoles had a 65% increased risk of the infection. About 52% of black women had the infection, compared with 27% of white women, the study found (Bakalar, New York Times, 5/26). The study found that 93% of women with BV had low vitamin D levels and that BV prevalence decreased as vitamin levels increased.In addition, although black women were more likely to have BV, white women who had low levels of vitamin D were as likely to have the infection as black women. Poor diets and obesity also contributed to a vitamin deficiency. Bodnar noted that black women are less likely than white women to meet dietary recommendations for vitamin D. Bodnar recommended that women discuss their level of vitamin D with their physicians and that pregnant women take a prenatal vitamin, which typically includes vitamin D.According to the Pittsburgh Post-Gazette, Bodnar"s research team has received NIH funding to conduct a study of whether vitamin D deficiency in women increases the risk of poor birth outcomes and whether high infant mortality among blacks can be attributed to factors such as obesity (Templeton, Pittsburgh Post-Gazette, 5/23).
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NIH Deepens Investment In Combination Study Of MS Drugs
The first large-scale "CombiRX" clinical trial testing the combined use of FDA-approved interferon beta-1a (Avonex®) and glatiramer acetate (Copaxone®) to treat relapsing-remitting MS has just received a $19-million renewal grant from the National Institutes of Health. This is the largest MS trial ever supported by the NIH, with a cumulative investment of more than $44 million. The long-term trial is led by principal investigator Fred Lublin, MD, (Corinne Goldsmith Dickinson Multiple Sclerosis Center at Mount Sinai School of Medicine, New York, NY).
Public Health

Use Of Lawyers Linked To Increased Health Care Utilisation Among Trauma Patients, Australia

A survey of trauma patients reported in the Medical Journal of Australia has found that compensation-related factors are significant predictors of health care utilisation. Ian Harris, Professor of Orthopaedic Surgery and Director of the University of New South Wales" South West Sydney Clinical School, and his colleagues approached patients on a hospital trauma database who had been admitted between 1 May 1999 and 30 April 2004. A total of 355 patients responded to the survey. After examining a broad range of variables, the results showed a definite correlation between compensation and utilisation of health care. "Most notably, we found a significantly higher utilisation rate among patients using a lawyer". This remained true "after allowing for the effects of time since injury, other compensation factors, injury severity, demographic factors and socioeconomic factors". "The reason for this effect is uncertain." The analysis "showed that use of a lawyer and claiming compensation both had a strong effect, but the effect of a compensation claim was not significant after allowing for use of a lawyer." "It is possible that patients with more severe conditions required more health care visits, and were more likely to have a complex claim ò€¦ however, we did not find that injury severity was a significant predictor of health care utilisation." The results also showed that a longer time since injury and having a head injury were significantly associated with lower health care utilisation, whereas being unemployed and having a chronic illness were associated with higher health care utilisation. Professor Harris said the study provided evidence showing both predisposing factors (such as age and chronic illness) and enabling factors (such as compensation) are significant predictors of health care utilisation. Medical Journal of Australia


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