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BioCis Pharma Starts A Phase I Clinical Trial With A New Cancer Drug
BioCis Pharma Ltd., a privately-held drug development company with its headquarters in Turku, Finland, has started Phase I clinical testing of ProtoCure(TM) intravesical instillation solution, a novel anti-cancer drug for urinary bladder cancer. ProtoCure is based on a new mechanism of action discovered and developed by BioCis Pharma which effectively prevents cancer growth and proliferation locally.
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New Study Reports Weight Change Significantly Impacts Quality Of Life ForType 2 Diabetes Patients
Type-2 diabetes patients who lose at least 5% of their body weight score significantly higher on health-related quality of life measures than those who gain 5%, according to a new Consumer Health Sciences (CHS) study presented today at the 14th Annual ISPOR (International Society for Pharmacoeconomic and Outcomes Research) Conference in Orlando, Florida. The benefits of weight loss are particularly dramatic for obese patients, who experience a sharp increase in quality of life scores with just a 5% weight reduction.
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Green Tea Compound May Block A Key Process In Alzheimer's Development
Researchers affiliated with Natura Therapeutics, Inc., Tampa, Florida, and the University of South Florida (USF) have jointly received a one-year, $110,000 Small Business Innovation Research (SBIR) grant from the National Institutes of Health"s (NIH) National Center for Complementary and Alternative Medicine to continue studying TeaMem™, a compound made from green tea.
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To Maintain Normal Daily Function, Those With Insomnia Need Increased Brain Activation

According to a research abstract presented at SLEEP 2009, the 23rd Annual Meeting of the Associated Professional Sleep Societies, patients suffering from chronic primary insomnia (PIs) have higher levels of brain activation compared to normal sleepers during a working memory test. Results show that PIs use increased brain activation relative to good sleepers during the working memory task, particularly in areas responsible for visual-spatial attention and coordination of cognitive processes. This activation may explain how PIs maintain performance on the task despite their sleep difficulties. PIs also were found to have decreased activation in visual and motor areas, which may suggest that PIs have higher baseline activation in these regions relative to good sleepers. According to principal investigator Henry Orff, MS, at the University of California in San Diego, Calif., these findings show that PIs, like individuals who are acutely sleep deprived, may be able to maintain performance on different tasks if they are able to compensate with increased brain activation. "The good news is that patients with insomnia are probably able to function well in their daily lives and likely do not show significantly impaired performance," said Orff. "That said, patients may have to work, concentrate, and attend more to tasks than people who sleep well." The study included 12 people with primary insomnia (six females) with an average age of 39.4 years, and nine good sleepers (four females) with an average age of 35.7 years. Performance was compared between the two groups on a working memory task. Functional MRIs (FMRI) taken during the task also were compared. Behavioral performance was measured by reaction time for correct responses, number of correct responses, and number of errors committed. The authors state that they do not know yet whether the findings suggest potential long-term implications for cognitive functioning in the future if primary insomnia is left untreated. Abstract Title: Insomnia Patients Show Increased Cerebral Activation when Compared to Good Sleepers during an NBack Working Memory Task Presentation Date: Tuesday, June 9 Category: Sleep Disorders - Insomnia Abstract ID: 0779 Kelly Wagner American Academy of Sleep Medicine


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