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Innovative Treatment Approach Offers New Hope For Eczema Sufferers With Moderate To Severe Disease
Today sees the European launch of the first topical calcineurin inhibitor to be approved for the maintenance treatment of eczema to prevent flares and prolong flare-free intervals. PROTOPIC ointment (tacrolimus monohydrate) is already licensed to treat moderate and severe eczema (atopic dermatitis), often involving the treatment of flares as and when they occur.* It is now also approved for twice-weekly application to previously affected skin to prevent these exacerbations and prolong flare-free periods in PROTOPIC-responsive patients.ò€  Clinical studies have shown that this new approach brings significant benefits with over 40% of patients with moderate to severe eczema remaining flare-free for at least a year.1 Flares are known to place an enormous burden on patients. The International Study of Life with Atopic Eczema (ISOLATE) found that about 55% of these patients worried about the onset of their next exacerbation and that they spent on average over a third of the year (136 days) with their eczema in flare.2
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Women With Breast Cancer Cope Better Following Program Focused On Body, Mind And Spirit
Pathfinders, a program designed to care for the whole person -- body, mind and spirit -- has been found to help women with terminal cancer cope and has improved their quality of life, according to a study led by researchers in the Duke Comprehensive Cancer Center.
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Data Demonstrates Long-Term Reduction In Seizure Frequency With Novel Once Daily Anti-Epileptic Zebinix(R)
Data presented yesterday, in Budapest, demonstrated that add-on treatment with the novel, once-daily anti-epileptic Zebinix®* (eslicarbazepine acetate; ESL) resulted in a marked and sustained decrease in seizure frequency over the long-term. Results from the one-year extension of a pivotal Eslicarbazepine Acetate phase III study were presented at the International Congress for Epilepsy in Budapest, Hungary. Patients not controlled with existing anti-epileptic drugs who were given eslicarbazepine acetate as an add-on treatment experienced a mean reduction in seizure frequency of more than 61% (95%CI: -68.2%, -55.5%). Nearly 65% of patients were classified as responders, meaning that they had achieved at least a 50% reduction in seizure frequency with Zebinix® treatment1.
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Somnia Anesthesia: 3rd Study Confirms Anesthesia Improves Outcomes In Colonoscopies

More pre-cancerous polyps were found in colonoscopies performed with deep sedation primarily using Propofol than with milder sedation in which patients remained conscious, according to a recent study conducted by Katherine Hoda, M.D. of Oregon Health and Science University. This improvement in cancer detection will save lives and reduce the number of patients requiring surgery and chemotherapy. The retrospective review of nearly 105,000 procedures shows doctors found polyps larger than 9mm or suspected colorectal tumors at a 25% higher rate in patients under deep sedation. This research further bolsters the near identical findings of two studies completed by the University of Pennsylvania and State University of New York. Those studies tracked facilities that switched from having the GI doctor perform the colonoscopy and also deliver the sedatives, to having an Anesthesiologist administer Propofol. The findings revealed the number and percentage of patients who had a polyp detected improved up to 43%. "25% and 43% improvements in cancer detection can"t be ignored. Finding cancer in its early stages saves lives and saves considerable medical costs," says Dr. Marc E. Koch, founder and CEO of Somnia Anesthesia. "What we are seeing here is the validation of two obvious points. First, that use of a potent anesthesia induction agent, which rapidly causes unconsciousness and immobility, should permit the colonoscopist to perform the procedure with greater efficacy since they are not trying to hit a moving target." "Second," adds Koch, "is that Colonoscopy patients receiving Propofol are deep asleep-probably just as asleep as a patient undergoing major or complex surgery. This is the very state that permits better viewing conditions for the endoscopist, and this is the very reason why an anesthesiologist or CRNA should be the professional administering it." Propofol is used for procedures including planned heart defibrillation, cardiac by-pass surgery and brain surgery; as well as for minor surgery where in smaller doses it causes light sedation. Its warning label clearly categorizes it as a powerful anesthetic and that those who administer it should 1) be trained in general anesthesia and 2) not performing the actual surgical procedure. Despite the improved results evident from these studies, occasional insurance companies have resisted payment for anesthesia and anesthesiologists for colonoscopies. "Catching cancer sooner clearly saves lives which is our primary goal," says Dr. Stanford Plavin, Vice Chairman of PreventingColorectalCancer.org, "but what is often overlooked is the benefit to the healthcare system. The cost of having an Anesthesiologist or CRNA administer Propofol is dwarfed by what patients and the healthcare system save when cancer is averted or detected so early." Somnia Anesthesia


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