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USA Today Examines 'Incendiary Debate' Over Abortion Rights
Nearly 40 years after the Supreme Court"s decision in Roe v. Wade, the "incendiary debate over abortion rights endures" and continues to manifest itself in a number of ways, USA Today reports. According to a recent USA Today/Gallup Poll, 78% of U.S. residents want abortion to be legal under at least some circumstances, with 21% saying it should be legal under any circumstance. According to the poll, 18% of respondents said that they want abortion always to be illegal. The poll also found that 46% of U.S. residents self-identify as "pro-choice," while 47% self-identify as "pro-life."Nancy Northup, president of the Center for Reproductive Rights, said, "The enduring divide represents the reality that there are fundamental religious differences on the issue of abortion that do not exist on, say, campaign finance or even on health care." Americans United for Life President Charmaine Yoest said that abortion-rights opponents are mobilizing to urge congressional lawmakers to exclude abortion coverage and funding from any federal health reform legislation.During the confirmation hearings of Supreme Court nominee Sonia Sotomayor, the judge said that she does not believe previous court rulings on abortion rights have ended the national controversy surrounding the issue. According to USA Today, Sotomayor, who has never ruled on the issue, declined to reveal her personal position on abortion rights. Several antiabortion-rights advocates also protested during Sotomayor"s hearings (Biskupic, USA Today, 7/24).In addition, the Center for Reproductive Rights this week released a report that found physicians and employees of health care clinics providing abortion services in six states -- Alabama, Mississippi, Missouri, North Dakota, Pennsylvania and Texas -- face an increasing level of harassment and death threats. The report was based on a four-month investigation (AP/Houston Chronicle, 7/23). The report was tied to the murder of Kansas abortion provider George Tiller (USA Today, 7/24). Operation Save America Director the Rev. Flip Benham, whose group is mentioned in the report, said the center is trying to limit the free-speech rights of abortion-rights opponents (AP/Houston Chronicle, 7/23).
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New Research Presented At EHA Congress Shows That Soliris(R) Significantly Reduced Hemolysis In Never-Transfused Patients With PNH
Clinical investigators observed that Soliris® (eculizumab), a first-in-class terminal complement inhibitor developed by Alexion Pharmaceuticals, Inc. (Nasdaq: ALXN), reduced hemolysis (red blood cell destruction) and improved symptoms in nine patients with paroxysmal nocturnal hemoglobinuria (PNH) who had received no blood transfusions prior to initiating Soliris therapy.
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Brain Activity Stablilized By Dynamic Molecular Mechanism
In the brain, many types of synaptic proteins are spatio-temporally regulated to maintain synaptic activity at a constant level. Here, the Japanese research group led by Professor Masaki Fukata, Drs. Yuko Fukata and Jun Noritake in National Institute for Physiological Sciences, Japan, found that two types of palmitoylating enzymes finely-tune the location and function of a major synaptic protein, PSD-95, in different ways. They also found that this mechanism contributes to keeping synaptic activity stable when synaptic activity dynamically changes. The Japan Science and Technology Agency (JST) supported this study. They report the finding in Journal of Cell Biology published on July 13, 2009.
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Skill Learning Imroved By Magnetic Brain Stimulation

The use of magnetic pulses to stimulate the dorsal premotor cortex (PMd) region of the brain results in an improved ability to learn a skilled motor task. Researchers writing in the open access journal BMC Neuroscience show that skilled movements can be stored as memories in the PMd and that magnetic stimulation of this area can facilitate this learning process. Lara Boyd and Meghan Linsdell, from the University of British Columbia, studied the effect of transcranial magnetic stimulation of the PMd on the ability of 30 volunteers to track a target on a computer screen using a joystick. During the task, the target would move randomly, then enter a programmed pattern and finally return to moving randomly. The participants were not aware of the repeated section, believing that movements were random throughout. The volunteers received four days of training, during which they were either given excitatory stimulation, inhibitory stimulation or sham stimulation immediately before practicing the motor task. The volunteers were not aware which group they were in. On the fifth day, they were tested to see how well they had learned the task. By comparing the improvements between the random and repeated sections of the task, the researchers were able to separate the general improvement due to practice from the learned motor memory of the repeated section. Those participants who had received the excitatory stimulation were significantly better than the other groups at tracking the target during the repeated section of the test. They showed no significant difference in improvement during the random sections. The researchers conclude, "Our data support the hypothesis that the PMd is important for continuous motor learning, specifically via off-line consolidation of learned motor behaviors". Notes: Excitatory repetitive transcranial magnetic stimulation to left dorsal premotor cortex enhances motor consolidation of new skills Lara A Boyd and Meghan A Linsdell BMC Neuroscience (in press) Graeme Baldwin BioMed Central


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