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Addex Partner Starts First-Ever Clinical Trial Of An MGluR Positive Allosteric Modulator
Allosteric modulation company Addex Pharmaceuticals (SWISS: ADXN) announced today that its partner Ortho-McNeil- Janssen Pharmaceuticals Inc. (OMP) has started Phase I testing of ADX71149, a metabotropic glutamate receptor 2 (mGluR2) positive allosteric modulator (PAM). This product, which has potential to treat schizophrenia, anxiety, depression and other CNS disorders, is the first PAM of any mGluR subtype to enter clinical trials. Targeting mGluR2 with a PAM is a novel approach that may offer advantages over classical drug approaches. In reaching this milestone, Addex received a EUR 1 million payment from OMP and remains eligible for additional development milestones and royalties.
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New Report Offers Policy Recommendations For Including Long-Term Care Services In Health Care Reform
The SCAN Foundation released a policy report by Georgetown University researchers presenting four distinct policy options for including long-term care support and services in health care reform. The report comes on the heels of a National Omnibus Survey on Long-Term Care released last week, also from The SCAN Foundation, showing that nearly 80 percent of Americans would be more likely to support a health care reform package that includes improved coverage for long-term care services.
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Meeting To Examine Human Behavior And The Threat Of Disease
As swine flu spread from Mexico to Texas and then fanned out farther in the United States, Americans began to alter their behavior. Families kept children home from school, postponed trips to the mall, and stayed home instead of eating out. In so doing, the American population may have inadvertently altered the behavior of the pathogen itself.
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New Jersey Senate Passes Bill Requiring Pharmacists To Tell Consumers If Generic Drugs Can Replace Brand-Name Prescriptions

The New Jersey Senate on Thursday unanimously passed legislation (A 2030) that would require pharmacists to inform consumers when they have substituted generic drugs for brand-name prescriptions, the Newark Star-Ledger reports. The General Assembly approved the legislation in February and it now moves to Gov. Jon Corzine (D).If Corzine signs the bill, the law would take effect within 180 days, making New Jersey the first state in the U.S. to have such a requirement. State Sen. Christopher Bateman (R) said, "We"re hoping that other states will follow our lead" (Megerian, Newark Star-Ledger, 5/22). Reprinted with kind permission from http://www.kaisernetwork.org. You can view the entire Kaiser Daily Health Policy Report, search the archives, or sign up for email delivery at http://www.kaisernetwork.org/dailyreports/healthpolicy. The Kaiser Daily Health Policy Report is published for kaisernetwork.org, a free service of The Henry J. Kaiser Family Foundation. © 2009 Advisory Board Company and Kaiser Family Foundation. All rights reserved.


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