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Reducing Drug Side-Effects In Pain Relief: New Research
They are a group of drugs which millions of people rely on to keep pain at bay but they can have unwanted side-effects which are sometimes more serious than the original health problem. Now scientists at The University of Nottingham are taking part in the largest-ever study on the safety of Non-Steroidal Anti-Inflammatory Drugs (NSAIDS) that has ever been performed.
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Eye Movements Of Parkinson's Disease Patients During Sentence Comprehension Support Subcortical Role In Processing Syntax
The study of the neural basis of language has largely focused on regions in the cortex - the outer brain layers thought by many researchers to have expanded during human evolution. Research at Brown University"s Department of Cognitive and Linguistic Sciences, reported in the September Issue of Cortex, published by Elsevier, adds to evidence that deeper, subcortical regions are also critical by pinpointing when Parkinson"s disease patients have difficulty while processing grammatically complex sentences. In Parkinson"s disease, degeneration of subcortical dopamine-secreting neurons leads not only to motor symptoms but often also to cognitive deficits.
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Editorial, Opinion Piece Respond To Closure Of Murdered Abortion Provider Tiller's Clinic
Two newspapers recently published an editorial and an opinion piece in reaction to the announcement that murdered Kansas abortion provider George Tiller"s Wichita clinic would be permanently closed. The clinic was one of a handful in the U.S. offering abortion procedures in the second and third trimesters. Summaries appear below.~ Kansas City Star: The closing of Tiller"s clinic is "a tragedy for American democracy," and the "irrational violence" of his death has "trumped public policy," a Star editorial states. "The basis of civilization is that we agree to submit to the rule of law in order for society to flourish," the editorial says, adding that Tiller"s murder is "antithetical to that principle. It is dismaying to see a killer achieve his objective." The editorial notes that Tiller provided abortion services in "tragic cases" involving women "at risk of infertility or death; fetuses with severe abnormalities; and victims of rape and incest." It continues that the "reduction or loss of that service will create hardships and may put women"s lives at risk." Hospitals and doctors who refer such cases to abortion providers "must reassess the circumstances under which they would perform late-term abortions," according to the editorial. In addition, the "medical profession must take a role in training and supporting doctors willing to provide abortions," and the government and local police "must do all they can to protect a legal medical practice," the editorial says. It concludes, "Democracy demands that we not allow murder to make de facto public policy" (Kansas City Star, 6/11).~ Eric Zorn, Chicago Tribune: The announcement that Tiller"s clinic will remain permanently closed "was simply more proof that violence and intimidation can get results where civil discourse and political process fail," Tribune columnist Zorn writes. "The question isn"t whether prominent foes of abortion rights are being honest with us when they decry Tiller"s violent death and express regret over the means used to achieve an end they"ve sought," Zorn writes, adding, "Some are, I"m sure." He continues that abortion-rights opponents "recognize that ... a movement calling itself "pro-life"can"t also be pro-murder" and "are politically savvy enough to know that the gains won by terrorist acts are grudging and difficult to sustain." He continues that to "make terrorism less effective, and thereby discourage it," abortion-rights advocates, the medical profession, politicians and law enforcement officials "need to reopen that clinic in Wichita and assure its safe operation ... to defy terrorism, if for no other reason." He concludes that "as long as abortion remains legal, this same coalition needs to strive to expand the number of facilities where it"s available" (Zorn, Chicago Tribune, 6/11).
Public Health

MedImpact Study Highlights Effects Of Value-Based Benefit Design On Adherence To Diabetes Medications

MedImpact researchers and Health Alliance Medical Plans, a MedImpact client, presented findings from an important new study that evaluates the impact of value-based benefit design (VBBD) on adherence to diabetes medications. Study results show that implementation of a VBBD program that reduced copayment by almost fifty percent for diabetic medications resulted in significantly improved medication adherence. VBBD, also known as value-based insurance design, is a new pharmacy benefit design that defines drug copay on clinical value rather than drug acquisition cost. The rationale behind VBBD is that many important treatments for chronic illnesses, such as diabetes and asthma, are often underused due to cost, leading to undesirable patient outcomes such as an increase in complications and preventable hospitalizations. The purpose of this research was to evaluate the impact of a VBBD on adherence to diabetes medications among a pilot group of Carle Clinic enrollees. The program reduced copayment for diabetic medications by 47.6 percent and improved the odds of adherence by 73.3 percent. The number of non-adherent patients was reduced by 33.4 percent. "This study adds to a growing body of evidence that shows adherence to treatment is higher when there are lower copays," said Dr. Robert Scully, senior medical director for Health Alliance Medical Plans. "Companies such as Pitney Bowes have reported that improved adherence after introduction of a VBBD for diabetic medications was followed by lower overall claim costs in their diabetic population. Our goal is to prove this in an insured population, and the pilot data we are reporting now is very encouraging." The MedImpact study-"The Impact of Formulary Value-Based Insurance Design on Adherence to Diabetes Medications: A Propensity Score Matched Difference in Difference Evaluation"-was presented at the International Society for Pharmacoeconomics and Outcomes Research (ISPOR) 14th Annual International Meeting on Tuesday, May 19. "ISPOR is an innovative, vital organization that supports the science of health economics and the effects of health care interventions on patient well-being," said Dr. Louis Brunetti, senior vice president and chief medical officer for MedImpact. "The research presented during the annual meeting is translated into valuable information for health care decision-makers and ultimately helps to better allocate scarce health care res." ISPOR represents researchers and practitioners, including pharmacists, physicians, and economists. The research findings benefit all members of the health care continuum, including hospitals, patients and managed care and pharmacy benefit design organization"s personnel, who use the information to make better informed health care decisions. About MedImpact Healthcare Systems, Inc. Headquartered in San Diego, MedImpact Healthcare Systems, Inc., is the nation"s largest pharmacy benefit management (PBM) company that does not sell drugs. Founded in 1989, the company currently serves more than 32 million individuals nationwide. MedImpact clients include Fortune 500 corporations and employers, unions, managed care organizations, insurance carriers, third-party administrators, as well as local, state and federal employee programs. MedImpact bases its success on delivering innovative products and services designed to lower overall client cost while increasing member satisfaction and quality of care. Health Alliance Medical Plans, Inc.


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