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In Thoracic Transplantation More Stringent Evaluation On The Use Of Generic Medications Recommended
A closer look at regulatory and clinical concerns with generic immunosuppression medications in thoracic transplantation is required, according to an educational advisory by the International Society for Heart and Lung Transplantation (ISHLT) in the July 2009 issue of The Journal of Heart and Lung Transplantation, published by Elsevier.
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Is It Legitimate To Stop Clinical Trials Early On Account Of Their "Opportunity Costs"?
A provocative debate in this week"s PLoS Medicine examines whether it
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Illumina Launches Multi-Sample Indexing For GoldenGate(R) Assay
Illumina, Inc. (NASDAQ:ILMN) launched GoldenGate Indexing, a high-throughput genotyping solution that utilizes multi-sample indexing technology. Researchers may now screen up to 16 times as many samples per reaction as the standard GoldenGate Assay, increasing throughput from 288 samples per day to greater than 2000, while decreasing total reagent consumption. This high-quality genotyping system includes automation control and positive sample tracking through an Illumina Laboratory Information Management System (LIMS), creating a turnkey solution for low-complexity screening at an affordable cost per sample. The plexity ranges include 96-plex, 192-plex and 384-plex, which are ideal for screening in the livestock and agriculture market as well as for whole-genome association target validation and quality control applications.
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Link Between Vitamin D And Reduction In Multiple Sclerosis Risk

Could a holiday in the sun reduce the risk of developing multiple sclerosis? In a recent review for F1000 Medicine Reports, Bridget Bagert and Dennis Bourdette highlight recent advances in potential treatments. Multiple sclerosis (MS) results from a failure of the body to recognize itself. The immune system attacks and destroys the sheath that protects nerve fibres, as if it were a foreign body or infection. Vitamin D, which is produced in the skin in response to natural sunlight, is an immune system regulator. This might explain why MS is less common in sunnier countries. Giving MS sufferers vitamin D pills - or encouraging them to spend more time in the sun - might be a cheap and easy treatment. Bagert and Bourdette point out that oral vitamin D therapy is now in phase II clinical trials, to see how well it works and how much would be needed. They say "The arrival of effective oral agents will give MS patients more therapeutic options and will be a major advance in the global effort to alter the natural history of this chronic disease". Dennis Bourdette, Faculty Member for F1000 Medicine, is chairman of the Department of Neurology and director of the Multiple Sclerosis and Neuroimmunology Center at Oregon Health and Science University, USA. Bridget A Bagert is a member of the Department of Neurology, Louisiana State University Health Sciences Center, USA The full text of this article is available at http://www.f1000medicine.com/reports/10.3410/m1-34/. Kathleen Wets Faculty of 1000: Biology and Medicine


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