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New Report Finds American Obesity Rates Climb Again - Fruits & Vegetables Important To Combating Obesity
Adult obesity rates did not decrease in a single state over the past year, but rather increased in 23 states. Also, the percentage of obese and overweight children is now at or above 30 percent in 30 states.
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Some Health Groups Increase Lobbying Spending, But Only A Slight Rise Overall
"Drug makers, advocacy groups, biotechnology firms and insurance companies have ratcheted up efforts to offer their two cents - and in most cases much, much more - in influencing the health care legislation now working its way through Congress," The New York Times reports. "Many familiar health groups in recent months have increased lobbying spending by more than $1 million, according to second-quarter lobbying records filed on Monday with the Senate Office of Public Records." Those groups include AARP and The Blue Cross and Blue Shield Association. Drug makers GlaxoSmithKline and Novartis, along with insurance company Allstate and biotechnology firm Amgen have also invested significantly more in lobbying activities."
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Drug Combination Improves Outcome For Advanced Non-Small Cell Lung Cancer
A new, international study found that the combination of two drugs delays disease progression for patients with advanced non-small cell lung cancer (NSCLC). Results from the Phase III "ATLAS" trial were presented today by Dr. Vincent Miller of Memorial Sloan-Kettering Cancer Center (MSKCC) at the American Society of Clinical Oncology Annual Meeting.
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Is It Possible To Differentiate GISTs From Leiomyomas By Endoscopic Ultrasonography?

A research article in the World Journal of Gastroenterology addresses this question. This research led by Professor Kim and his colleagues in Pusan National University, South Korea. They evaluated the EUS features of gastric GISTs in comparison with gastric leiomyomas, and tried to determine the EUS features that could predict the malignant potential of gastric GISTs according to the histological risk classification. In their study, to differentiate GISTs from leiomyomas by EUS, the following four features were helpful; inhomogenicity, hyperechogenic spots, a marginal halo and higher echogenicity as compared with the surrounding muscle layer. These features appeared more frequently in GISTs than in leiomyomas. The presence of at least two of these four features had a sensitivity of 89.1% and a specificity of 85.7% for predicting GISTs. Except for tumor size and irregularity of the border, most of the EUS features were not helpful in predicting the malignant potential of GISTs. On multivariate analysis, only the maximal diameter of the GISTs was an independent predictor. The optimal size for predicting malignant GISTs was 35 mm. The sensitivity and specificity using this value were 92.3% and 78.8%, respectively. Gastric mesenchymal tumors are often asymptomatic, and they are usually incidentally discovered during upper gastrointestinal endoscopy for unrelated conditions. The main problem in the asymptomatic patient is to determine whether or not the tumors have a malignant potential. Because GISTs have malignant potential, gastric mesenchymal tumors, even if they are small, should not be ignored if the EUS features are suggestive of GISTs. Even though, there are already a large number of publications on the EUS-features of stromal cell tumors available, this research would provide an additional clinical approach guideline in patients with gastric mesenchymal tumors. Reference: Kim GH, Park DY, Kim S, Kim DH, Kim DH, Choi CW, Heo J, Song GA. Is it possible to differentiate gastric GISTs from gastric leiomyomas by EUS? World J Gastroenterol 2009; 15(27): 3376-3381 http://www.wjgnet.com/1007-9327/15/3376.asp Lin Tian World Journal of Gastroenterology


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