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EMEA Grants Clinuvel New Orphan Drug - For Solar Urticaria - Designation
Clinuvel Pharmaceuticals Limited (ASX: CUV; XETRA-DAX: UR9; ADR: CLVLY) is pleased to announce that afamelanotide, its photoprotective drug, has been granted Orphan Medicinal Product (OMP) designation by the European Medicines Agency (EMEA) for the treatment of Solar Urticaria (SU). The EMEA granted afamelanotide its first OMP designation in March 2008 for the treatment of Erythropoietic Protoporphyria (EPP), Clinuvel"s lead indication currently in Phase III clinical trials.
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Tadalafil (Cialis) In The Treatment Of Erectile Dysfunction
UroToday.com - This updated review of tadalafil (Cialis), one of the three available phosphodiesterase type 5 (PDE5) inhibitors that revolutionized the treatment of erectile dysfunction (ED), analyzes its latest clinical studies. Tadalafil"s most unique and identifying characteristic is its long half-life of 17.5 hours, compared with 4 hours for sildenafil (Viagra) and vardenafil (Levitra).
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Poor Birth Outcomes Increased By Lower Legal Drinking Age, Study Finds
Amid renewed calls to consider reducing the legal drinking age, a new University of Georgia study finds that lower drinking ages increase unplanned pregnancies and pre-term births among young people.
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Illumina Launches Multi-Sample Indexing For GoldenGate(R) Assay

Illumina, Inc. (NASDAQ:ILMN) launched GoldenGate Indexing, a high-throughput genotyping solution that utilizes multi-sample indexing technology. Researchers may now screen up to 16 times as many samples per reaction as the standard GoldenGate Assay, increasing throughput from 288 samples per day to greater than 2000, while decreasing total reagent consumption. This high-quality genotyping system includes automation control and positive sample tracking through an Illumina Laboratory Information Management System (LIMS), creating a turnkey solution for low-complexity screening at an affordable cost per sample. The plexity ranges include 96-plex, 192-plex and 384-plex, which are ideal for screening in the livestock and agriculture market as well as for whole-genome association target validation and quality control applications. Livestock geneticists, including Curt Van Tassell of the USDA Agricultural Research Service, worked with Illumina to develop GoldenGate Indexing and are now working on a custom panel for screening livestock. Replacing older methods will allow livestock screening labs to better access genetic information of value. For example, breeders use SNP data to identify DNA markers for applications such as identifying parentage and economically important traits, including disease resistance, marbling, and feed efficiency. With Illumina"s new GoldenGate Indexing, researchers will have a higher degree of multiplexing options at a cost they can afford. "Both livestock and crop researchers have a vested interest in adopting low-plex, high-sample throughput genotyping as a more efficient method for screening. GoldenGate Indexing offers genetic laboratories the opportunity to expand their existing efforts in molecular breeding with a low-cost, fully automated system for fixed and custom content studies," said Joel McComb, senior vice president and general manager of Illumina"s Life Sciences business unit. The Illumina GoldenGate Assay is a flexible, pre-optimized assay providing consistent, high-quality genotyping results. GoldenGate Indexing leverages this proven technology by evolving it into a high-sample throughput solution with fully integrated automation and sample tracking capabilities. GoldenGate Indexing represents only one aspect of Illumina"s broad portfolio of genetic analysis tools for human and agricultural research. Illumina"s array and sequencing-based technologies support the industry"s broadest range of genetic analysis applications. For more information, please visit http://www.illumina.com/goldengateindexing. Illumina


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