Popular Articles
Cellulite Treatment

Sen. Sessions To Give Floor Speeches On Judiciary As GOP Prepares For Sotomayor Debate
Sen. Jeff Sessions (R-Ala.), the ranking member on the Senate Judiciary Committee, on Wednesday is expected to outline the Republican Party"s vision for the judiciary and the kinds of judges the GOP supports for the Supreme Court in the first of a series of floor speeches, according to committee s, Roll Call reports. Although the speeches are not directly targeted at Supreme Court nominee Judge Sonia Sotomayor, Sessions said he hopes they will begin a "national dialogue" on the judiciary"s role ahead of her confirmation hearing, which is scheduled to begin July 13. Sessions is expected to give four to five speeches, which also will appear as opinion pieces in the Washington Times this week. His first speech will address his views on the foundation of a strong judiciary and judicial restraint. The later speeches will focus on President Obama"s call for judges who display "empathy" and other issues, according to Roll Call. The committee said the speeches "will address the fundamental issues that will be in play during the confirmation process" and "make the case for judicial restraint versus judicial activism."According to Roll Call, part of Sessions" motivation for giving the speeches is to clarify the definition of terms like "judicial restraint," "activist judge" and "empathy standard," phrases that frequently arise in debates over judges but might not be widely understood among judicial outsiders and the general public. Senators are expected to question Sotomayor on such topics during her confirmation hearing, and Sessions aims to define the context of the terms before the hearings begin, Roll Call reports. Senate Judiciary Committee Chair Patrick Leahy (D-Vt.) said that he is optimistic that Sotomayor"s hearings will remain bipartisan and that Republicans would not attempt to derail them by boycotting the hearings. He added that he believes GOP senators will participate in the hearings despite their complaints that they have not had enough time to prepare (Stanton, Roll Call, 6/17).
generic viagra online
Data Demonstrates Long-Term Reduction In Seizure Frequency With Novel Once Daily Anti-Epileptic Zebinix(R)
Data presented yesterday, in Budapest, demonstrated that add-on treatment with the novel, once-daily anti-epileptic Zebinix®* (eslicarbazepine acetate; ESL) resulted in a marked and sustained decrease in seizure frequency over the long-term. Results from the one-year extension of a pivotal Eslicarbazepine Acetate phase III study were presented at the International Congress for Epilepsy in Budapest, Hungary. Patients not controlled with existing anti-epileptic drugs who were given eslicarbazepine acetate as an add-on treatment experienced a mean reduction in seizure frequency of more than 61% (95%CI: -68.2%, -55.5%). Nearly 65% of patients were classified as responders, meaning that they had achieved at least a 50% reduction in seizure frequency with Zebinix® treatment1.
News of the day
Study Could Help Target New Pancreatitis Treatments
Pancreatitis is often a fatal condition, in which the pancreas digests itself and surrounding tissue. Scientists have previously found that alcohol can trigger the condition by combining with fatty acids in the pancreas, which leads to an excessive release of stored calcium ions. Once calcium ions enter cell fluid in the pancreas it activates digestive enzymes and damages the cells.
Medical Devices

Gene Increases Risk Of Cancer

Scientists discover novel mechanism that increases the risk of common colorectal cancer Finnish Academy Professors Lauri Aaltonen and Jussi Taipale have identified and described a mechanism whereby a single-base change in the human genome increases the risk of colorectal cancer. The focus in this study was on a common single-base variant occurring in chromosome 8, which in itself causes only a slightly increased risk of cancer. However, the risk allele is carried by 75% of people of European origin and by almost 100% of African populations. The high frequency of the gene variant makes it a very common cause of cancer at the population level. At the individual level, however, the variant does not cause significant disease predisposition because that can often be considerably reduced by lifestyle changes. Colorectal cancer is the third most common cancer worldwide and a major cause of cancer mortality. Mutation mechanisms activate pathways regulating cancer The variant that increases the risk of colorectal cancer was found to be located in a regulatory region, where it changes the function of a key regulatory element important for the development of colorectal cancer. The scientists showed that the risk allele strengthens the binding of a regulatory factor in cancer cells, which activates pathways that are central to the development of cancer. The impacts of this altered genetic regulation on cell division are probably mediated via the MYC cancer gene, which is one of the best known accelerator genes in cancer. Single-base changes are the most common type of variation found in the human genome. Genome-wide studies of interindividual differences in common variants can be studied using DNA chip technology, which has greatly facilitated efforts to understand the genetic basis of multifactorial diseases. To date, scientists have identified more than 400 variants in the human genome that are associated with an increased risk of common diseases, such as cancer, diabetes and cardiovascular diseases. Multidisciplinary research The findings of this research lend support to the theory that human disease susceptibility is explained in part by differences in regulatory regions of the genome, and in gene expression. A closer understanding of the biological mechanisms involved will help to clarify the aetiology of colorectal cancer and pave the way to more effective cancer prevention. Apart from hereditary tumor predisposition, another area of major strength for Finnish research is gene regulation. It was hardly surprising therefore that Aaltonen"s and Taipale"s research teams found each other so easily. The research project supervised by Aaltonen and Taipale involved molecular biologists, medical doctors and data processing researchers from Finland and the UK. For instance, the project made use of the EEL software developed by Professor Esko Ukkonen and his team at the CoE for Algorithmic Data Analysis. The research was funded by the Academy of Finland, the European Union, the Sigrid Juselius Foundation and the Cancer Foundation. The results of the study will be published in the prestigious journal Nature Genetics. www.nature.com/ng/ DOI 10.1038/ng.406 Academy Professor Lauri Aaltonen Academy of Finland


Add your comment:
Name:
Site address: http://
Your message:
Enter today\\\\'s date, 2 digits
(spam protection):