Categories
Cardiovascular
Diagnostics
Endocrinology
Health Insurance
Medical Devices
Mental Health
Nutrition
Oncology
Public Health
Sexual Health
Popular Articles
Cellulite Treatment

Emerging Techniques Put A New Twist On Ankle Repair
People with ankle injuries who do not respond successfully to initial treatment may have a second chance at recovery, thanks to two new procedures developed to restore the injured area, according to a study published in the July 2009 issue of the Journal of the American Academy of Orthopaedic Surgeons (JAAOS).
generic viagra online
Researcher Works To Help Mexican Americans With Type 2 Diabetes
Starr County, Texas, sits on the Texas-Mexico border along the banks of the Rio Grande River. Populated largely by Mexican Americans, it is a rural county where some of the residents live in colonias, unincorporated areas with no city services. The county seat, Rio Grande City, is home to approximately 15,000 people. Scratch the surface and Starr County has one surprising distinguishing feature: one of the highest prevalence rates of type 2 diabetes in the entire country, and the highest diabetes death rate in Texas.
News of the day
GOP Letter To Obama Urges 'Common Ground' On Health Reform, Restrictions On Abortion Funding
House Republicans on Wednesday sent President Obama a letter urging "open and constructive dialogue across party lines" on health care reform and calling on him to maintain current restrictions on federal funding of abortion services, Politico reports. The letter, signed by House Minority Leader John Boehner (Ohio), House Minority Whip Eric Cantor (Va.), House Republican Conference Chair Mike Pence (Ind.) and six other Republican House members, outlines the Republicans" positions on health care reform. It says achieving those objectives "can be accomplished through health reform that maintains current law provisions regarding restrictions on federal funding of abortion services, restricts federal funds from flowing to abortion providers and does not impose mandates either on insurance carriers or medical providers to participate in activities that violate their religious and moral beliefs."The letter says that Republicans have several "areas for potential common ground on health care reform." In all, it mentions the phrase "common ground" four times in eight paragraphs, Politico reports (Allen, Politico, 5/13).
Sexual Health

Focusing On The More Lethal Form Of The Cancer Rhabdomyosarcoma

Rhabdomyosarcoma (RMS) is an aggressive muscle cancer that mostly affects children. The most common forms of RMS are embryonal rhabdomyosarcoma (ERMS) and alveolar rhabdomyosarcoma (ARMS). Although ARMS is less common than ERMS, it is associated with a much higher rate of mortality. A therapy tailored to the ARMS form of RMS is therefore badly needed. A team of researchers, at the Hospital for Sick Children, Toronto, and Monash Institute of Medical Research, Australia, has now provided hope that it might be possible to develop such a therapy by showing that the protein ILK promotes the growth of ARMS cells, whereas it suppresses the growth of ERMS cells. The team, led by David Malkin and Gregory Hannigan, determined that the signaling protein JNK mediated these differing effects of ILK. Knocking down expression of ILK in ERMS cells induced activation of JNK and promoted tumor cell growth both in vitro and when the cells were transplanted into immunodeficient mice. Conversely, knocking down expression of ILK in ARMS cells abrogated both JNK signaling and tumor cell growth. Further analysis revealed that the protein product of the fusion gene that characterizes ARMS downregulated JNK1 expression, providing mechanistic insight into the opposing roles of ILK in ARMS and ERMS. The authors therefore suggest it should be possible to identify patients with ARMS who would benefit from an anticancer therapeutic that targets ILK. In an accompanying commentary, Charles Keller and colleagues concur with the authors that targeting ILK might provide a therapeutic strategy tailored to the treatment of ARMS. However, they caution that further studies are needed, in part because of the high rate of misdiagnosis of ARMS versus ERMS. TITLE: JNK1 determines the oncogenic or tumorsuppressive activity of the integrin-linked kinase in human rhabdomyosarcoma AUTHOR CONTACT: David Malkin Hospital for Sick Children, Toronto, Ontario, Canada. Gregory E. Hannigan Monash Institute of Medical Research, Melbourne, Victoria, Australia. ACCOMPANYING COMMENTARY TITLE: Integrin-linked kinase: both Jekyll and Hyde in rhabdomyosarcoma AUTHOR CONTACT: Charles Keller University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA. Karen Honey Journal of Clinical Investigation


Add your comment:
Name:
Site address: http://
Your message:
Enter today\\\\'s date, 2 digits
(spam protection):

© Copyright 2009