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Link Between Migraines And Reduced Breast Cancer Risk Confirmed In Follow-up Study
The relationship between migraine headaches in women and a significant reduction in breast cancer risk has been confirmed in a follow-on study to landmark research published last year and conducted by scientists at Fred Hutchinson Cancer Research Center. The new study found a 26 percent reduced risk of breast cancer among both premenopausal and postmenopausal women with a clinical diagnosis of migraines.
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UVA Study Shows Early Success In Treating Deadly Brain Tumors
New research from the University of Virginia Health System shows that, when combined, two emerging medical technologies hold significant promise for treating the most deadly and devastating form of brain tumor, glioblastoma multiforme (GBM).
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Appeals Court Upholds Massachusetts Law Establishing Protest-Free Zone Around Abortion Clinics
The U.S. Court of Appeals for the 1st Circuit on Wednesday ruled that a 2007 Massachusetts law requiring antiabortion-rights protesters to stay at least 35 feet away from clinic entrances does not infringe on their free speech rights, the Boston Globe reports. The law updated a 2000 statute that established a floating buffer zone, which police and clinics said was difficult to enforce. The 2007 law set a fixed 35-foot buffer zone around any reproductive health care facility and barred anyone from entering or remaining in the zone unless they work at the clinic; are entering or leaving the facility; are public safety or other municipal officials; or are walking by. Five abortion-rights opponents filed the lawsuit in January 2008. U.S. District Judge Joseph Tauro rejected their claims in August 2008, ruling that the law did not regulate speech -- only the location where the speech could occur -- and that it was drafted in response to safety and law enforcement concerns. The protesters appealed the ruling.The appeals court said that the 2007 law responded to "repeated incidents involving violence and other unduly aggressive behaviors in the vicinity of reproductive health care facilities" and "represents a permissible response by the Massachusetts Legislature to what it reasonably perceived as a significant threat to public safety." The court also said that the law was "content-neutral," as it applies to all protesters regardless of their viewpoints. According to the court, the plaintiffs argued in their appeal that the law had a "content-neutral patina" masking a "more sinister reality" that the Legislature"s true motive was to curb abortion-rights opponents" speech.Massachusetts Attorney General Martha Coakley (D) in a statement said that she was "pleased that the 1st Circuit has upheld this important law, which enhances public safety and access to medical facilities, while preserving the right to engage in expressive activity on public ways and sidewalks near clinics." Tim Chandler, legal counsel for the Alliance Defense Fund, which helped represent the plaintiffs, said abortion-rights opponents "shouldn"t be penalized for expressing their beliefs." He added that the fund and its supporters were evaluating the "next legal step" (Finucane, Boston Globe, 7/10).
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Children With Sickle Cell Disease Need A Good Night's Sleep

Children with sickle cell disease tend to have interrupted sleep many times during the night leaving them tired and irritable during the day. It may be because the oxygen levels in their blood are reduced or they tend to have enlarged adenoids and tonsils, which can interfere with breathing at night. Whatever the cause, the mystery is about to be solved thanks to a groundbreaking study set to start at Barts and The London NHS Trust Children"s Hospital into airway blockage during sleep in pre-school children with sickle cell disease (distorted red blood cells) and how this may contribute to serious health problems later in life. Results from the two-year study, the first of its kind in the United Kingdom, could have significant implications for the treatment of sickle cell disease patients throughout the world and will enable doctors to start treatments earlier, such as removing tonsils or providing night-time oxygen face masks. The study, supported by a grant of ÷£160,566 from Barts and The London Charity, brings together haematologists and sleep researchers and will make use of the paediatric sleep service"s laboratory facilities at The Royal London Hospital, Whitechapel, east London. Pre-school children will be videoed and recordings taken of their breathing rate, heart rate, blood oxygen levels and physical activity during the night. To assess if low oxygen in the blood is common in young children with sickle cell disease, the study will measure blood oxygen during sleep in all young children registered with the Barts and The London paediatric sickle cell service. Around 12,000 people in the UK, including 300 babies every year in England, have sickle cell disease, which particularly affects African and Afro-Caribbean populations. The disease is one of the most common reasons for repeated hospital admissions in these ethnic groups. About 75% of these are in London. In east London and Essex alone there are about 70-80 cases per year. Professor Jonathan Grigg, Consultant Paediatrician and Principal Co-Investigator of the study said: "Use of the sleep laboratory facilities will generate a much more detailed set of data - other studies have tended to use simple equipment to measure blood oxygen levels. "The study aims to recruit 90-100 patients from the local community, plus around 60 control patients (of similar age and ethnic background but without sickle cell disease). It will also look at the genes involved in the body"s inflammatory response to see if a genetic pre-disposition could explain why only some patients are affected. "Children with sickle cell disease often develop enlarged adenoids and tonsils, which can interfere with breathing at night. As a result, they may awake briefly from sleep many times during the night, as oxygen levels in the blood may be reduced leaving children chronically tired during the day. "Compared with other genetic conditions, sickle cell disease is a neglected disease. Few studies have looked at problems with breathing in patients with sickle cell disease, and fewer still have explored this in young children." There are about 800 children in east London with sickle cell and about 350 of them are looked after and managed at The Royal London Hospital, Whitechapel. There is a clinical network for ensuring good care throughout the region and The Royal London is the specialist centre for the network. Other hospitals include Homerton, Newham, Whipps Cross, Queens Romford, Basildon, Harlow, and Southend. Notes 1. Because of mutations affecting haemoglobin, the oxygen-carrying pigment in blood, red blood cells become distorted ("sickle"). Sickled cells can block blood vessels, causing episodes of pain and may lead to other complications, such as lung damage and stroke. There are many triggers for attacks of sickling, including low oxygen levels in the blood. - Barts and The London is one of Britain"s top teaching hospital trusts. Our mission is literally to bring excellence to life - to give patients the best possible care so that they can live better, fuller, longer lives. - Our world-renowned hospitals - St Bartholomew"s (Barts) in the City, The Royal London in Whitechapel and The London Chest in Bethnal Green - have made and continue to make an outstanding contribution to modern medicine. Read more about our full portfolio of services at http://www.bartsandthelondon.nhs.uk. - Our ÷£1 billion new hospitals programme is set to transform healthcare facilities locally. When completed the new hospital at The Royal London will be the biggest new hospital in the country, while the new buildings at Barts will house a brand-new cancer hospital and cardiac centre. Barts and The London NHS Trust


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