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Novel Discovery In Dendritic Cell Signalling Pathways Pave The Way For New Therapeutic Targets
Scientists from A*STAR"s Singapore Immunology Network (SIgN) and the University of Milano-Bicocca, Italy, have discovered another signaling pathway for the activation and apoptosis, or programmed cell death, of dendritic cells[1] . This discovery was published in the advanced online publication of Nature on 15 Jun 2009.
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Researchers At The University Of Tennessee Health Science Center Begin New Study On Parkinson's Disease
Researchers at the University of Tennessee Health Science Center (UTHSC) are recruiting participants for a national clinical study of medication that could slow the progression of Parkinson"s disease. The study, referred to as "QE3," will examine the effectiveness of the research medication Coenzyme Q10 (CoQ). During the study, investigators will administer high doses of CoQ to participants 30 years of age or older with early stage Parkinson"s disease to reduce the speed of their physical decline. The research is sponsored by the National Institute of Neurological Disorders and Stroke, a division of the National Institutes of Health (NIH), and will be conducted by the Parkinson Study Group, an international council of physicians and researchers experienced in caring for Parkinson"s patients and studying the disease.
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An Aspirin A Day Brings No Clear Benefits To Healthy People
UK researchers who reviewed pooled clinical trial data covering 95,000 people concluded that there was no net benefit to healthy people taking
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CardioNet Announces Launch Of Clinical Indicator For Sleep Disorders

CardioNet, Inc. (NASDAQ:BEAT) announced the launch of SomNet ™, a new clinical indicator available in the Company"s existing Mobile Cardiac Outpatient Telemetry™ (MCOT™) system. Because many patients with cardiac disorders also suffer from common sleep disorders like sleep apnea, CardioNet believes that SomNet has the potential to identify patients with a high likelihood of such sleep disorders by measuring cyclic variation of heart rate (CVHR), a rhythm that is caused by repeated arousals from sleep due to such disorders. SomNet"s utility is based on data presented at the Heart Rhythm Society"s (HRS) 30th Annual Scientific Sessions in Boston. "There is a high prevalence of sleep disorders like sleep apnea in the cardiovascular and arrhythmia population," said Randy Thurman, CEO of CardioNet. "The data collected by SomNet is extremely valuable information that can be captured from our existing MCOT ECG signal. If clinically appropriate, physicians may choose to refer patients with CVHR patterns to sleep centers for further diagnostic testing, to determine if they have sleep apnea or another serious sleep disorder." In an 80-patient study presented today at HRS, Phyllis K. Stein, Ph.D., Research Associate Professor of Medicine at Washington University School of Medicine, found that automated identification of clinically relevant CVHR is feasible using CardioNet"s MCOT system. The study compared MCOT automatic analysis of CVHR patterns versus a human expert"s direct analysis of plots of HR patterns for measuring clear (large amplitude) CVHR. Findings showed similar specificity and positive predictive value measures between MCOT and human expert analysis, with slightly lower sensitivity measures for the automated analysis. "Although slightly less sensitive than more labor intensive human overreading, the MCOT system and SomNet may provide a platform for efficiently identifying patients with severe sleep disorders, like sleep apnea, in a large population," said Dr. Stein. CardioNet, Inc.


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