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Seniors Defend Medicare Advantage Plans
USA Today reports that Medicare Advantage, which allows seniors to buy Medicare coverage through private insurance companies, could provide one of the largest spending cuts for Congress to pay for an overhaul of the health care system though "President Obama has called (it) a "wasteful" subsidy for the health insurance industry. ... Debate over Medicare Advantage, which has 10.2 million enrollees - about one-fifth of all Medicare participants - illustrates a broader struggle Congress and Obama face as they look for ways to pay for a $1 trillion overhaul of health care without raising taxes on the middle class or compromising care. It has raised concerns among some seniors who might have to pay more for the program or enroll in regular Medicare instead."
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Management Insights Study Warns That State Privacy Rules Reduce Electronic Medical Sharing
States that have passed privacy laws restricting the ability of hospitals to disclose patient information have seen the sharing of electronic medical records suffer by more than 24%, according to the Management Insights feature in the current issue of Management Science, the flagship journal of the Institute for Operations Research and the Management Sciences (INFORMS®).
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Pediatric Obstructive Sleep Apnea Treated Effectively By Surgery
Infants and young toddlers with obstructive sleep apnea and sleep disordered breathing experience significant improvement following surgical treatment of the ailment, according to an invited article in the June 2009 issue of Otolaryngology-Head and Neck Surgery.
Mental Health

Blood Flow In Alzheimer's Disease

Dr. Jennifer C Palmer and colleagues at the University of Bristol have discovered that endothelin converting enzyme-2 (ECE-2) may cause the decrease in cerebral blood flow seen in Alzheimer"s disease. These results are presented in the July 2009 issue of the American Journal of Pathology. Alzheimer"s disease is the most common form of dementia. Aí² peptide, which accumulates in the brain of Alzheimer"s disease patients, is thought to lead to tightening of the blood vessels and reduction of cerebral blood flood. ECE-2 may contribute to these symptoms by converting an inactive precursor to endothelin-1, which constricts blood vessels. To determine if ECE-2 affects cerebral blood flow in Alzheimer"s disease, Palmer et al examined the expression of ECE-2. They found that ECE-2 levels were elevated in patients with Alzheimer"s disease and that Aí² could increase ECE-2 expression in vitro. These data indicate that ECE-2 levels are increased in response to Aí² and may cause the decrease in cerebral blood flow seen in Alzheimer"s disease. Palmer et al "suggest that [endothelin-1] receptor antagonists, already licensed for treating other diseases, could be of benefit in [Alzheimer"s disease] therapies." Palmer JC, Baig S, Kehoe PG, Love S: Endothelin-Converting Enzyme-2 is Increased in Alzheimer"s Disease. Am J Pathol 2009, 174: 2672-2680 Angela Colmone American Journal of Pathology


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