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Research Into Genetic Neurological Disorders Will Benefit From New Mouse Model
Neurosensory diseases are difficult to model in mice because their symptoms are complex and diverse. The genetic causes identified are often lethal when transferred to a mouse. The lack of animal models slows progress in understanding and treating the diseases. By strategically altering a protein-making molecule, a mouse was made to help understand nervous system diseases that impair feeling and cause paralysis of the arms and legs in humans.
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Pharmaceutical Company Manager Sentenced For Off-Label Marketing
A Branchburg, NJ, woman was sentenced for violating the Food, Drug and Cosmetic Act, for marketing the drug Bextra for uses and dosages that were not approved by the Food and Drug Administration.
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IOM Comparative Effectiveness Research Priorities Report
A new report from the Institute of Medicine recommends 100 health topics that should get priority attention and funding from a new national research effort to identify which health care services work best. It also spells out actions and res needed to ensure that this comparative effectiveness research initiative will be a sustained effort with a continuous process for updating priorities as needed and that the results are put into clinical practice.
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Bipolar Disorder 'misdiagnosed In A Quarter Of Cases'

Bipolar disorder is misdiagnosed as depression in over a quarter of cases, a new study suggests. The research is presented today at the Royal College of Psychiatrists" 2009 Annual Meeting in Liverpool. Psychiatrists Dr Krishna Gangineni and Dr Richard Annear, who work in Wales, reviewed the medical notes of people referred to psychiatric services for assessment. They found that over 25% of the patients with bipolar disorder had initially had their condition misdiagnosed as unipolar depression. Misdiagnosis often occurs because the symptoms of bipolar disorder overlap with depression and other psychiatric disorders. However, misdiagnosis can cause serious problems. For example, if people are wrongly prescribed antidepressants this can make their bipolar illness worse. Dr Gangineni and Dr Annear said: "Our study found that bipolar disorder was misdiagnosed as unipolar disorder in more than 25% of the patients who first see a mental health professional. "Recognition of bipolar disorder and its adequate treatment is paramount because bipolar disorder exacts such as a high personal and societal toll, with high rates of suicide and interpersonal problems and a substantial economic burden." Reference: Annual Meeting of the Royal College of Psychiatrists, BT Convention Centre, Liverpool, 2 -5 June 2009 Royal College of Psychiatrists


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